Every human being, until the moment of redemption, is under the domain of darkness and the dominion of sin - John MacArthur

"Every human being, until the moment of redemption, is under the domain of darkness and the dominion of sin. The unbeliever is wholly corrupted by the bondage of his fallen condition and utterly unable to free himself from it. Not surprisingly, the very notion of such absolute enslavement (a doctrine commonly known as 'total depravity' or 'total inability') is repugnant to the fallen human heart. In fact, no doctrine is more hated by unbelievers than this one, and even some Christians find it so offensive that they zealously attack it." 

~ John MacArthur, "Slave," p. 121.